Delta 8 THC is becoming more and more popular among medical marijuana patients, but many do not know what it is or the benefits. Delta 8 THC is one of 113 cannabinoids in cannabis plants. Some of the most popular cannabinoids are delta 9 THC (responsible for psychoactive effects), cannabinol (CBN) (used for pain relief), cannabidiol (CBD) (used to treat seizures, nausea, anxiety disorders), and cannabigerol/beta-caryophyllene (CBG) which has anti-inflammatory properties that can be used to help with cancer treatment side effects such as nausea. Delta 8 wholesale does not produce any psychoactive effects because it does not bind CB1 receptors in the brain like delta 9 THC. This cannabinoid is used for many medical benefits like anti-cancer, stimulates bone growth, and helps with PTSD (1).
Delta 8 THC has been found to be effective in fighting breast cancer. Delta 8 THC inhibits breast cancer cell proliferation by inhibiting DNA synthesis via the mammalian target of rapamycin (mTOR) pathway through which it also inhibits beta-lactamase production from A549 human lung adenocarcinoma cells(2). In another study delta 9 THC successfully inhibited leukemia cell growth but research on delta 8 THC for this treatment was not mentioned(3). Bulk delta 8 cart Hemp Products may help fight ovarian cancer because they have been shown to slow pancreatic tumor growth and increase apoptosis of pancreatic tumor cells(4). Delta 8 THC has also been used to inhibit tumor growth in glioblastoma cells(5).
Delta 8 THC is also effective for stimulating bone growth. The CB2 cannabinoid receptor, which delta 8 THC activates, plays an important role in the regulation of skeletal development (6). It was found that delta 8 THC promoted osteocyte differentiation and mineralization by upregulating Wnt ligands (7). This means that delta 8 THC can help decrease the effects of osteoporosis which causes bones to become brittle because there are less number of active osteoblasts or it allows them do their job better than usual.
People who suffer from PTSD may benefit from using delta 8 THC. Cannabis-induced analgesia is partially mediated by the CB1 receptor in similar to opioid analgesic effects. The treatment of PTSD has long been hampered because of this fact, but delta 8 THC does not stimulate cannabinoid receptors but still produce an anti-anxiety effect which is beneficial for patients with PTSD(8).
Delta 8 THC also reduces pain caused by chemotherapy. Delta 8 THC was suggested as a potential medication for neuropathic pain which is caused by chemotherapy (9). Symptoms of gastrointestinal toxicity among cancer patient are treated with cannabinoid agonists that can be used to treat nausea in chemo patients in addition to its well known use to help increase appetite.